Bioanalysis, Metabolism

Modern bioanalytical methods for the quantitation of drug compounds, bio molecules (peptides) in biological fluids, or tissues require combined mass spectrometric and chromatographic techniques. These techniques are chosen for their inherent sensitivity and specificity of detection.

With over 25 years experience in mass spectrometry, a staff of post-graduate and PhD scientists and an array of instrumentation (including HPLC-MS/MS, UPLC-MS/MS and GC-MS), SGS M-Scan provides high quality bio-analytical services, including metabolism and pharmacokinetics. SGS M-Scan is particularly aware of the need for rapid turnaround of samples, so that key decisions can be made quickly, as well as the need for flexibility to meet our client requirements. Areas of expertise in bioanalysis include:

  • Method Validation to ICH / FDA / EU requirements
  • Hepatocytes / microsome stability
  • Plasma and tissue analysis
  • Metabolite Identification from in vitro / in vivo samples