SGS M-Scan has developed methods for the analysis of extractables and leachables from food packaging and pharmaceutical container and closure systems.
Multiple extraction solvents with a range of boiling points and polarities, together with multiple extraction techniques selected from reflux, soxhlet extraction and ultrasonication are utilised to maximise the breadth of extraction conditions.
These conditions are designed to extract:
- Phthalates and other plasticisers
- Vulcanisation agents and accelerators e.g. mercaptobenzothiozole (MBT)
- Antioxidants, light stabilisers and polymer-processing additives
- PAH from carbon black
- Oligomeric compounds
- Trace metals
- Nitrosamine from sulphur cured rubbers
- Ink and adhesive from secondary packaging (e.g. labels)
The wide range of chromatography and mass spectrometry instrumentation including GC-MS, LC-ESMS, LC-APCIMS, LC-MSMS, Evolved Gas Analysis Mass Spectrometry and ICP available to SGS M-Scan enables all these extractables, and others, to be analysed.