Circular Dichroism (CD)
SGS M-Scan’s Wokingham facility is the first in the UK to offer GLP/GMP-compliant Circular Dichroism Analysis (CD), and the first to install Jasco’s latest CD Spectropolarimeter, the J-815, with class leading optical performance versatile for a range of applications, including:
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Protein folding and conformational studies (secondary structure)
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DNA/RNA interactions
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Enzyme kinetics
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Purity testing of optically active substances
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Quantitative analysis of pharmaceuticals
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Natural organic chemistry
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Biochemistry and macromolecules
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Rapid scanning (time resolved) experiments
This is a significant enhancement to SGS M-Scan’s Product Characterisation Package, tailored to the ICH Q6B guideline which require Spectroscopic Profiling as part of the assessment of the physicochemical properties of a product. All new biotechnological or biological products need spectroscopic profiling as proof of conformance to gain regulatory approval.
 Near UV CD 'Fingerprinting' of different batches |
 Far UV Circular Dichroism of different batches |
SGS M-Scan also offers research level NMR for spectroscopic profiling.
