Analysis of Process-Related Impurities and Contaminants in Biotech or Biological Products
At SGS M-Scan process-related impurities and contaminants are isolated and analysed using a combination of analytical techniques such as:
Analysis of cell substrate-derived impurities and contaminants
Cell substrate-derived impurities include host cell proteins and host cell DNA. Please contact us to discuss options.
Analysis of cell culture-derived impurities and contaminants
At SGS M-Scan, we have experience in analysing cell culture-derived impurities and contaminants. Examples include, but are not limited to, antibiotics (e.g. Kanamycin), inducers (e.g. IPTG), media components, etc.
Analysis of downstream-derived impurities and contaminants
Downstream-derived impurities and contaminants include, but are not limited to, enzymes, residual solvents, leachables and detergents (e.g. PEG, TWEEN). SGS M-Scan are experienced in both routine analysis and “trouble-shooting.”